About Me

I recently completed my M.S. in Medical Physics at Duke University, where I was advised by Prof. Fang-Fang Yin. I am an incoming Ph.D. student in the Shanghai Jiao Tong University U-EIT program, advised by Prof. Jingxu (Jesse) Zhu and Prof. Donovan Chaffart.

My research bridges medical physics, photochemistry, particle and fluid systems, and AI-assisted molecular design. I am particularly interested in building experimentally grounded computational platforms for radiotherapy phantoms, tetrapyrrole photophysics, and molecular property prediction. I received my joint Bachelor's training in Materials Science and Engineering at the Southern University of Science and Technology and Yunnan University. During my undergraduate research at SUSTech, I worked in Prof. Yanqing Tian's group at the Organic Polymer Functional Materials Laboratory. I also previously worked with the Electronic Materials and Devices Group at YNU.

News & Updates

Publications

Journal Articles

  1. Guofan Zhang, Xuanzhi Wang, Qirui Sun, Hanchi Zhao, Jiaao Han, Haoyuan Yang, Hanyu Wang, Chengshu Tian, Aizhen Kuang, Chulong Zhang, Tianhao Li, Zijing Wang, Pengzhan Guo, Rui Liu. A versatile method for accurately predicting electronic absorption spectra of tetrapyrrole macrocycles. Scientific Reports 2026. https://doi.org/10.1038/s41598-026-55436-6Accepted 25 May 2026. Published 11 June 2026.
  2. Guofan Zhang†*, Tan Zhang, Fang-Fang Yin*. A roadmap for the implementation of 3D-printed organs in healthcare. Device 2025, 100847. https://doi.org/10.1016/j.device.2025.100847First and corresponding author.
  3. Shaoyong Cai, Guofan Zhang, Lei Wang, Tianlan Jian, Jiatong Xu, Fengyu Su, Yanqing Tian. Ratiometric fluorescent sensor based on TPU-PVP coaxial nanofibers for monitoring trace ammonia in breath. Materials Today Chemistry 26 (2022), 101148. https://doi.org/10.1016/j.mtchem.2022.101148Co-first author.
  4. Shaoyong Cai, Guangjie Song, Guofan Zhang, Lei Wang, Tianlan Jian, Jiatong Xu, Fengyu Su, Yanqing Tian. A multicolor fluorescent sensor array based on curcumin and its analogs as a shrimp freshness indicator. Sensors and Actuators B: Chemical 367 (2022), 132153. https://doi.org/10.1016/j.snb.2022.132153
  5. He Zhang, Fangyuan Sun, Ge Cao, Dongyan Zhou, Guofan Zhang, Fengyu Su, Yanqing Tian, Yanhong Tian. Bifunctional flexible electrochromic supercapacitors based on silver nanowires flexible transparent electrodes. International Journal of Extreme Manufacturing 5 (2023), 015503. https://doi.org/10.1088/2631-7990/aca638
  6. Ge Cao, Jiatong Xu, Shaoyong Cai, Guofan Zhang, Yonghao Chen, He Zhang, Yanqing Tian. Highly conductive and dispersible PANI microtubes prepared in the presence of methyl orange. ACS Applied Polymer Materials 4 (2022), 5674-5682. https://doi.org/10.1021/acsapm.2c01674
  7. Min Shen, Hongtian Liu, Tingting Pan, Juewei Ning, Dongyan Zhou, Guangjie Song, Yuguo Wang, Shaoyong Cai, Xi Xia, Guofan Zhang, Fengyu Su, Yanqing Tian. Crosslinked PVA electrospinning nanofibrous film as a new platform for the design of K+ sensor. Sensors and Actuators B: Chemical 380 (2023), 133317. https://doi.org/10.1016/j.snb.2023.133317

Preprints

  1. Guofan Zhang et al. A Modular Web Platform for Porphyrin Molecular Design and UV-Vis-NIR Spectral Prediction in the Photosciences. ChemRxiv (2026). https://chemrxiv.org/doi/full/10.26434/chemrxiv.15001143/v1

Patents

  1. Yanqing Tian, Shaoyong Cai, Guofan Zhang, Ziqiang Wang. Curcumin derivative-based double-emission ratiometric fluorescence sensor and preparation. CN114634523 A (2022).
  2. Yanqing Tian, Shaoyong Cai, Guangjie Song, Guofan Zhang. Fluorescent ink and preparation method and application. CN114031977 A (2021).
Author notes

Co-first author. * Corresponding author.

Research Experience

3D-Printed Lung Phantoms, DKU/Duke

Prepared lung phantoms that simulate respiratory motion for radiotherapy dose verification. Work included 3D printing method evaluation, light-curing polymer preparation, and dose-verification use cases.

AI-predicted UV-Vis Spectra, DKU

Developed ML workflows for molecular absorption spectra from SMILES, including RDKit and DFT conformer pipelines, DTW/RMSE evaluation, Bayesian HPO, KAN exploration, and molecular embeddings.

Curcumin Derivatives for Breath NH3 Sensing, SUSTech

Designed BFC derivatives and ratiometric fluorescence probes, including TPU/PVP coaxial nanofiber construction and clinical feasibility exploration for Helicobacter pylori breath monitoring.

Multicolor Fluorescent Sensor Array, SUSTech

Fabricated visual sensing labels and evaluated photophysical and sensing properties for real-time shrimp freshness monitoring.

Skills

Experimental

UV-VisFluorometrySEMEDSXRDFTIRNMR

Computation

PythonLinuxMATLABChemDrawSOLIDWORKSOriginMestReNovaMDI Jade

Research Areas

Medical PhysicsRadiotherapy QA3D PrintingPhotochemistryTetrapyrrolesMolecular ML

Education

  • Duke University. M.S., Medical Physics. Aug 2024 to May 2026.
  • Yunnan University. B.Eng., Materials Science and Engineering, Joint Undergraduate. Sep 2023 to Jul 2024.
  • Southern University of Science and Technology. Study in Materials. Sep 2020 to Jul 2022.
  • Yunnan University. Early coursework. Sep 2019 to Jun 2020.

Honors, Awards & Funding

  • Blue Ribbon Poster, Therapy track, AAPM Annual Meeting, Vancouver, 2026.
  • Invited Report, Chinese Materials Conference, 2025.
  • Data+X (DIRC) and DII Cohort II, 2025.
  • Provincial Outstanding Graduate, approximately 0.5%, 2023.
  • China National Scholarship, approximately 0.2%, 2022.
  • University First-class and Second-class Scholarships, YNU, 2020 to 2022.
  • Micro-photography and Metallography contest awards, SUSTech/YNU, 2021 to 2022.

Conferences & Activities

Conferences

  • Oral Abstract. AAPM Annual Meeting, Vancouver, 2026.
  • Blue Ribbon Poster, Therapy track. AAPM Annual Meeting, Vancouver, 2026.
  • Oral/Poster. ACS 150 and 35th Chinese Chemical Society Annual Meeting, Chongqing, 2026.
    An Integrated Computational Platform for Predicting Electronic Absorption Spectra of Porphyrin and Related Tetrapyrrole Systems.
  • Oral Abstract. 22nd International Symposium on Organometallic Chemistry, Kyoto, 2025.
  • Poster. 9th International Symposium on Space Radiation Research and Particle Radiotherapy, Suzhou, 2024.
  • Poster. 23rd National High-tech Ceramics Academic Annual Conference, Hangzhou, 2024.

Teaching & Service

  • Teaching Assistant for CHEM 110 and CHEM 150, Dec 2024 to May 2026.
  • Volunteer, SUSTech Volunteer Union, 33.5 accumulated hours, Sep 2020 to Sep 2022.
  • Volunteer leader, 11th Guangdong University Student Material Innovation Competition, Nov 2021 to Jan 2022.

Contact

Email: guofan.zhang@duke.edu. ORCID: 0000-0002-1995-5355. Location: Durham, NC.